Matchups › Cassiopeia › vs Orianna

Cassiopeia vs Orianna

CassiopeiaYOU · MID
OriannaENEMY · MID
VS
Heavily unfavoredPre-6 HardPost-6 HardTake Teleport

How to play it

Respect her ult
Her R fires from where her ball is, so keep distance from the ball; Flash out if it catches you.
Punish her E cooldown
While her E shield is down she has no resistances: trade then, especially if her Q is also on CD.
Block her Q
Her Q deals less the more minions it passes through, so keep a minion between you and her ball.
Never linger near her ball while her ult is up: it fires from the ball and cuts off your escape.
Runes
SORCERYSORCERY
Summon Aery
Arcane Comet
Stormraider's Surge
Deathfire Touch
Axiom Arcanist
Manaflow Band
Nimbus Cloak
Transcendence
Celerity
Absolute Focus
Scorch
Waterwalking
Gathering Storm
PRECISIONPRECISION
Absorb Life
Triumph
Presence of Mind
Legend: Alacrity
Legend: Haste
Legend: Bloodline
Coup de Grace
Cut Down
Last Stand
SHARDS
Adaptive
Attack Speed
Ability Haste
Adaptive
Move Speed
Health Scaling
Health +65
Tenacity
Health Scaling
Spells
FlashFLASH
TeleportTELEPORT
Items
Start
Core
16.14 Emerald+ - 55% WR - 282 games
Skill order
123456789101112131415161718
QQQQQ
WWWWW
EEEEE
RRR
MAXEEQQWW
Cassiopeia · Mid · Patch 26.17 · Ranked Solo · Updated Sep 5, 2026

Cassiopeia vs Orianna in Mid lane is a hard lane on patch 26.17. The one thing to respect: her ult fires from her ball and cuts off your escape, stay clear of the ball.

Cassiopeia matchup data compiled from the contributions of Cassiopeia OTP mainsLeague of Legends assets © Riot Games (Data Dragon).