Matchups › Cassiopeia › vs Diana

Cassiopeia vs Diana

CassiopeiaYOU · MID
DianaENEMY · MID
VS
Swings with levelsPre-6 EasyPost-6 MediumTake Teleport

How to play it

Bait her Q
Crescent Strike is what starts her all-in by resetting her E: while that Q is down she barely threatens you.
W then R post-6
When she has kill threat, open W into R: if she Q's or E's toward you she's stunned, if not she's slowed and grounded.
Outrange her E
Your max-range Q slightly outranges Lunar Rush, so poke with it and walk in and out to fish her Q.
Never try to reactively stun her mid-E: she can turn instantly on landing, so aim where she'll land instead.
Runes
SORCERYSORCERY
Summon Aery
Arcane Comet
Stormraider's Surge
Deathfire Touch
Axiom Arcanist
Manaflow Band
Nimbus Cloak
Transcendence
Celerity
Absolute Focus
Scorch
Waterwalking
Gathering Storm
PRECISIONPRECISION
Absorb Life
Triumph
Presence of Mind
Legend: Alacrity
Legend: Haste
Legend: Bloodline
Coup de Grace
Cut Down
Last Stand
SHARDS
Adaptive
Attack Speed
Ability Haste
Adaptive
Move Speed
Health Scaling
Health +65
Tenacity
Health Scaling
Spells
FlashFLASH
TeleportTELEPORT
Items
Start
Core
Last 30 days Emerald+ - 48% WR - 1.1k games
Skill order
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QQQQQ
WWWWW
EEEEE
RRR
MAXEEQQWW
Cassiopeia · Mid · Patch 26.17 · Ranked Solo · Updated Sep 5, 2026

Cassiopeia vs Diana in Mid lane is a lane that swings with levels on patch 26.17. The one thing to respect: her all-in needs her Q to land, it resets her E, so bait it out and she has little threat.

Cassiopeia matchup data compiled from the contributions of Cassiopeia OTP mainsLeague of Legends assets © Riot Games (Data Dragon).